{"id":48838,"date":"2026-04-12T19:37:07","date_gmt":"2026-04-12T19:37:07","guid":{"rendered":"https:\/\/foreignnewstoday.com\/?p=48838"},"modified":"2026-04-12T19:37:07","modified_gmt":"2026-04-12T19:37:07","slug":"theres-a-very-clear-reason-why-some-people-live-to-100","status":"publish","type":"post","link":"https:\/\/foreignnewstoday.com\/?p=48838","title":{"rendered":"There&#8217;s a &#8216;very clear&#8217; reason why some people live to 100"},"content":{"rendered":"<p><br \/>\n<\/p>\n<div>\n<p>The age-old fixation.<\/p>\n<p>Hitting 100 rotations around the sun is no small feat, with just an <a href=\"https:\/\/www.pewresearch.org\/short-reads\/2024\/01\/09\/us-centenarian-population-is-projected-to-quadruple-over-the-next-30-years\/\" target=\"_blank\" rel=\"noopener\">estimated 101,000 centenarians<\/a>, representing 0.03% of the US population.<\/p>\n<p><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acel.70409\" target=\"_blank\" rel=\"noopener\">New research<\/a>, though, may have cracked the code for why some live to triple digits, and others don\u2019t.<\/p>\n<figure class=\"wp-block-image aligncenter size-large\"><button class=\"button button--modal-trigger\" aria-label=\"Open the image in a modal.\" data-modal-image=\"39065004\"><br \/>\n\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"icon-plus\" fill=\"#fff\" viewbox=\"0 0 1033 1000\" width=\"1em\" height=\"1em\"><path d=\"M380 364V0h273v355h380v290H653v355H380V645H0V355h380v9z\"\/><\/svg><br \/>\n<\/button><br \/>\n<figcaption>While very few live to 100, a new study has found a clue why some people reach centenarian status and others don\u2019t. <span class=\"credit\">Hunor Kristo \u2013 stock.adobe.com<\/span><\/figcaption><\/figure>\n<p>Lifestyle habits are often the primary drivers of longevity, such as regular exercise and healthy eating, as well as genetics playing a role.<\/p>\n<p>Researchers from the\u00a0University of Geneva\u00a0and the\u00a0University of Lausanne in Switzerland wanted to answer why some reach centenarian status  \u2014 and discovered the answers are in our blood.<\/p>\n<aside class=\"single__inline-module aligncenter wp-block-nypost-editor-primary-tag\">\n<\/aside>\n<p>The team analyzed blood samples of centenarians, octogenarians and adults aged 30 to 60. Measuring 724 proteins in the blood serum, they discovered that centenarians age differently at the molecular level.<\/p>\n<p>Those who reached 100 had 37 proteins that closely resemble those found in younger individuals,\u00a0including ones linked to inflammation and cardiovascular health.<\/p>\n<figure class=\"wp-block-image aligncenter size-large\"><button class=\"button button--modal-trigger\" aria-label=\"Open the image in a modal.\" data-modal-image=\"39065005\"><br \/>\n\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"icon-plus\" fill=\"#fff\" viewbox=\"0 0 1033 1000\" width=\"1em\" height=\"1em\"><path d=\"M380 364V0h273v355h380v290H653v355H380V645H0V355h380v9z\"\/><\/svg><br \/>\n<\/button><br \/>\n<img loading=\"lazy\" style=\"aspect-ratio:1.50146628;display:block\" loading=\"lazy\" decoding=\"async\" data-modal-image=\"39065005\" width=\"886\" height=\"590\" src=\"https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?w=1024\" alt=\"Lab technician holding a blood tube sample for study.\" class=\"wp-image-39065005\" srcset=\"https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?quality=75&amp;strip=all 5360w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=300,200&amp;quality=75&amp;strip=all 300w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=768,512&amp;quality=75&amp;strip=all 768w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=1024,682&amp;quality=75&amp;strip=all 1024w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=1536,1024&amp;quality=75&amp;strip=all 1536w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=2048,1365&amp;quality=75&amp;strip=all 2048w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=600,400&amp;quality=75&amp;strip=all 600w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=878,585&amp;quality=75&amp;strip=all 878w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=744,496&amp;quality=75&amp;strip=all 744w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=720,480&amp;quality=75&amp;strip=all 720w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=576,384&amp;quality=75&amp;strip=all 576w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=457,305&amp;quality=75&amp;strip=all 457w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=440,293&amp;quality=75&amp;strip=all 440w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=424,282&amp;quality=75&amp;strip=all 424w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=389,260&amp;quality=75&amp;strip=all 389w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=360,240&amp;quality=75&amp;strip=all 360w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=340,227&amp;quality=75&amp;strip=all 340w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=320,213&amp;quality=75&amp;strip=all 320w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=314,209&amp;quality=75&amp;strip=all 314w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=306,204&amp;quality=75&amp;strip=all 306w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=280,187&amp;quality=75&amp;strip=all 280w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=260,174&amp;quality=75&amp;strip=all 260w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=246,164&amp;quality=75&amp;strip=all 246w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=234,156&amp;quality=75&amp;strip=all 234w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=195,130&amp;quality=75&amp;strip=all 195w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=180,120&amp;quality=75&amp;strip=all 180w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=171,114&amp;quality=75&amp;strip=all 171w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=160,107&amp;quality=75&amp;strip=all 160w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=144,96&amp;quality=75&amp;strip=all 144w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=107,71&amp;quality=75&amp;strip=all 107w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=93,62&amp;quality=75&amp;strip=all 93w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=84,56&amp;quality=75&amp;strip=all 84w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=60,40&amp;quality=75&amp;strip=all 60w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=105,70&amp;quality=75&amp;strip=all 105w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=81,54&amp;quality=75&amp;strip=all 81w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=200,133&amp;quality=75&amp;strip=all 200w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=231,154&amp;quality=75&amp;strip=all 231w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=322,215&amp;quality=75&amp;strip=all 322w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=662,441&amp;quality=75&amp;strip=all 662w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=90,60&amp;quality=75&amp;strip=all 90w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=120,80&amp;quality=75&amp;strip=all 120w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=1200,800&amp;quality=75&amp;strip=all 1200w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=1038,692&amp;quality=75&amp;strip=all 1038w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=87,58&amp;quality=75&amp;strip=all 87w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=50,33&amp;quality=75&amp;strip=all 50w, https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2026\/04\/hands-lab-technician-tube-blood-125513443.jpg?resize=150,100&amp;quality=75&amp;strip=all 150w\" sizes=\"auto, (max-width: 886px) 100vw, 886px\"\/><figcaption>Those who were centenarians had 37 proteins in their blood that are also found in the blood of those decades younger. <span class=\"credit\">angellodeco \u2013 stock.adobe.com<\/span><\/figcaption><\/figure>\n<p>The proteins all play different yet important roles in the body.<\/p>\n<p>Five of the proteins were linked to oxidative stress, an imbalance between rogue free radicals and protective antioxidants in the body, which speeds up aging and fuels chronic diseases like\u00a0<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2990475\/\" target=\"_blank\" rel=\"noreferrer noopener\">cancer<\/a>,\u00a0<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10453126\/\" target=\"_blank\" rel=\"noreferrer noopener\">diabetes<\/a>\u00a0and\u00a0<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2675154\/\" target=\"_blank\" rel=\"noreferrer noopener\">Alzheimer\u2019s<\/a>.<\/p>\n<p>\u201cThe answer is very clear:\u00a0centenarians have significantly lower levels of antioxidant proteins than the standard geriatric population,\u201d said <a href=\"https:\/\/www.unige.ch\/sih\/hub\/team\/kkh\" target=\"_blank\" rel=\"noreferrer noopener\">Karl-Heinz Krause<\/a>, professor emeritus at UNIGE\u2019s Faculty of Medicine and co-author of the study.<\/p>\n<aside class=\"single__inline-module alignright\">\n\t<\/aside>\n<p>\u201cAt first glance this seems counterintuitive, but it shows that because oxidative stress is so much lower, they simply need fewer antioxidant proteins to keep it in check,\u201d he added.<\/p>\n<p>The researchers also found that regulatory proteins in the extracellular matrix, which help keep tissues strong, stayed at the same youthful levels seen in much younger participants.<\/p>\n<p>Proteins tied to\u00a0<a href=\"https:\/\/nypost.com\/2025\/03\/03\/health\/scientists-figured-out-how-to-trick-metabolism-for-weight-loss\/\">fat metabolism<\/a>, which normally spike with age, also rose far less in the centenarian group. <\/p>\n<p>Even DPP-4, a protein that breaks down GLP-1 \u2014 a hormone that boosts insulin and is the target of\u00a0<a href=\"https:\/\/nypost.com\/health\/what-is-glp-1-drug-how-does-it-work\/\">new diabetes and obesity drugs<\/a>\u00a0\u2014 stayed intact, helping centenarians\u2019 metabolism run more smoothly.<\/p>\n<p>\u201cBy breaking down GLP-1, DPP-4 helps keep insulin levels relatively low, which could protect against hyperinsulinism and\u00a0<a href=\"https:\/\/nypost.com\/2026\/01\/21\/health\/nearly-90-of-adults-have-some-form-of-this-silent-disease\/\">metabolic syndrome<\/a>,\u201d Delhaes explained.<\/p>\n<p>The researchers said the study highlights the importance of a healthy lifestyle for aging, as our lifestyle choices affect the majority of how long we live.<\/p>\n<p>\u201cPhysical activity helps maintain the extracellular matrix in a more \u2018youthful\u2019 state,\u201d the study authors noted. \u201cAnd avoiding excess weight also helps preserve a healthy metabolism, similar to that observed in centenarians.\u201d<\/p>\n<\/p><\/div>\n<p><br \/>\n<br \/><a href=\"https:\/\/nypost.com\/2026\/04\/12\/health\/theres-a-very-clear-reason-why-some-people-live-to-100\/\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The age-old fixation. Hitting 100 rotations around the sun is no small feat, with just an estimated 101,000 centenarians, representing 0.03% of the US population. New&hellip;<\/p>\n","protected":false},"author":1,"featured_media":48839,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[42],"tags":[],"class_list":["post-48838","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-wellness"],"_links":{"self":[{"href":"https:\/\/foreignnewstoday.com\/index.php?rest_route=\/wp\/v2\/posts\/48838","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/foreignnewstoday.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/foreignnewstoday.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/foreignnewstoday.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/foreignnewstoday.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=48838"}],"version-history":[{"count":0,"href":"https:\/\/foreignnewstoday.com\/index.php?rest_route=\/wp\/v2\/posts\/48838\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/foreignnewstoday.com\/index.php?rest_route=\/wp\/v2\/media\/48839"}],"wp:attachment":[{"href":"https:\/\/foreignnewstoday.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=48838"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/foreignnewstoday.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=48838"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/foreignnewstoday.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=48838"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}