{"id":6238,"date":"2026-02-27T06:34:11","date_gmt":"2026-02-27T06:34:11","guid":{"rendered":"https:\/\/foreignnewstoday.com\/?p=6238"},"modified":"2026-02-27T06:34:11","modified_gmt":"2026-02-27T06:34:11","slug":"four-supplement-combos-that-are-bad-for-your-brain","status":"publish","type":"post","link":"https:\/\/foreignnewstoday.com\/?p=6238","title":{"rendered":"Four supplement combos that are bad for your brain"},"content":{"rendered":"<p><br \/>\n<br \/><\/p>\n<div>\n<p>Not all supplements are super for your health.<\/p>\n<p>In fact, in the wrong dose or combined with the wrong stuff, some supplements can actually do more damage than repair.<\/p>\n<p>The rise of TikTok docs, pseudo sponsorships with influencers and <a href=\"https:\/\/nypost.com\/2026\/01\/14\/health\/inside-the-peptide-gray-market-where-people-are-diy-ing-glp-1s-and-botox\/\">gray market sales<\/a> has led to an explosion of misinformation around dietary supplements \u2014\u00a0or the more concentrated forms of the vitamins and minerals we already get from food \u2014 and their long term efficacy and safety.<\/p>\n<figure class=\"nyp-slideshow-modal-image wp-block-image aligncenter size-large\"><figcaption>Some neurologists are waving red flags about what they\u2019re calling \u201csupplement-induced accelerated aging.\u201d <span class=\"credit\">KMPZZZ \u2013 stock.adobe.com<\/span><\/figcaption><\/figure>\n<p>And medical doctors have taken note.\u00a0<\/p>\n<p>\u201cThe general principle emerging from the literature is that indiscriminate supplementation, particularly with isolated nutrients at high doses or in unbalanced combinations, may be more problematic than beneficial,\u201d Dr. Jerold Fleishman, MD, emeritus chief of neurology at MedStar Franklin Square and associate neurology professor at MedStar Georgetown University Hospital, <a href=\"https:\/\/parade.com\/health\/supplement-combinations-that-make-brain-age-faster\" target=\"_blank\" rel=\"noopener\">recently told Parade<\/a>.\u00a0<\/p>\n<p>\u201cThe safest approach remains obtaining nutrients through dietary patterns rather than supplements, with supplementation reserved for documented deficiencies under medical supervision.\u201d<\/p>\n<p>Without medical oversight, patients might accidentally get too much of a certain nutrient, to the point that it becomes toxic. And certain combinations in particular can wreak havoc on your brain, despite being otherwise mostly safe to use.\u00a0<\/p>\n<aside class=\"single__inline-module aligncenter wp-block-nypost-editor-primary-tag\">\n<\/aside>\n<p>These nasty combos can result in anything from premature brain aging to memory loss and seizures.<\/p>\n<p>While many of the following supplements can have benefits when administered on their own, you might want to leave the mixing and matching to your stylist. These are the supplement combinations doctors want you to be wary of.<\/p>\n<h2 class=\"wp-block-heading\"><strong>1. 5-HTP + St. John\u2019s wort<\/strong><\/h2>\n<p>Sometimes you <em>can<\/em> have too much of a good thing.\u00a0<\/p>\n<p>Serotonin syndrome, a drug reaction resulting in a dangerous build-up of serotonin in the body, is associated with the improper use of certain supplements used to treat conditions like depression, including St. John\u2019s wort and 5-HTP (also known as 5-Hydroxytryptophan).<\/p>\n<p>While some serotonin is essential for cell health and brain functioning, too much can <a href=\"https:\/\/www.cedars-sinai.org\/stories-and-insights\/healthy-living\/how-to-spot-and-prevent-serotonin-syndrome\" target=\"_blank\" rel=\"noopener\">overwhelm the brain<\/a>, according to Cedars-Sinai pharmacy specialist Chau Chu, and lead to complications.\u00a0<\/p>\n<figure class=\"nyp-slideshow-modal-image wp-block-image aligncenter size-large\"><figcaption>Serotonin syndrome, sometimes triggered by combining supplements that treat depression, can \u201coverwhelm the brain.\u201d <span class=\"credit\">amixstudio \u2013 stock.adobe.com<\/span><\/figcaption><\/figure>\n<p>On the mild end, that could look like shivering or diarrhea. On the severe end, however, <a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/serotonin-syndrome\/symptoms-causes\/syc-20354758\" target=\"_blank\" rel=\"noopener\">the Mayo Clinic warns<\/a> that patients could experience muscle rigidity, fever and seizures, and, if left untreated, death.<\/p>\n<p>Memorial Sloan Kettering <a href=\"https:\/\/www.mskcc.org\/cancer-care\/integrative-medicine\/herbs\/5-htp-01\" target=\"_blank\" rel=\"noopener\">warns<\/a> that 5-HTP should be \u201cavoided if taking other supplements\u201d such as St. John\u2019s wort or SAM-e, another supplement sometimes used to treat mental health disorders, \u201cbecause these products may also affect serotonin levels.\u201d<\/p>\n<aside class=\"single__inline-module alignright\">\n\t<\/aside>\n<h2 class=\"wp-block-heading\"><strong>2. Vitamin E + fish oil or ginkgo<\/strong><\/h2>\n<p>While all three of these supplements can be individually beneficial for overall brain health \u2014 as well as skin and eye health in the case of vitamin E, and heart health in the case of fish oil \u2014 together they can have the opposite effect.<\/p>\n<p>Each of the three contains anticoagulant properties. When combined, they could thin the blood to the point of causing a hemorrhagic stroke, which can contribute to vascular cognitive impairment (a form of accelerated brain aging) and chronic memory issues.<\/p>\n<p>Dr. Rob Nawaz Kahn, a neurologist, recently explained the dangers of combining fish oil and gingko in a supplement \u201cstack\u201d to Parade.\u00a0<\/p>\n<figure class=\"nyp-slideshow-modal-image wp-block-image aligncenter size-large\"><figcaption>Though it has benefits on its own for the heart and brain, when combined with other anticoagulants, too much fish oil can lead to internal bleeding or stroke. <span class=\"credit\">shulevich \u2013 stock.adobe.com<\/span><\/figcaption><\/figure>\n<p>\u201cThe worst combinations are the ones that raise bleeding risk or trigger dangerous stimulation,\u201d he said. \u201cA common risky stack is high dose fish oil plus ginkgo plus garlic or turmeric, especially if the person also takes aspirin, clopidogrel, warfarin or apixaban, because it can increase bruising and bleeding risk.\u201d<\/p>\n<p>The Cleveland Clinic <a href=\"https:\/\/my.clevelandclinic.org\/health\/drugs\/vitamin-e\" target=\"_blank\" rel=\"noopener\">also states<\/a> that overuse of vitamin E supplements is dangerous \u201cbecause your body stores vitamin E in your tissues and liver and doesn\u2019t eliminate extra amounts through your pee.\u201d\u00a0<\/p>\n<p>An overdose of vitamin E, more than 1,000 milligrams (mg) per day, could lead to brain bleeds.<\/p>\n<h2 class=\"wp-block-heading\"><strong>3. Copper + Zinc<\/strong><\/h2>\n<p>High-dose zinc can interfere with copper absorption because the two nutrients are absorbed by the same part of the gut, according to Pieter Cohen, MD, an associate professor of medicine at Harvard Medical School.\u00a0<\/p>\n<p>Copper deficiencies are linked to white matter degeneration, which causes cognitive decline (memory loss, slow processing), motor dysfunction (imbalance, gait issues) and emotional changes.<\/p>\n<figure class=\"nyp-slideshow-modal-image wp-block-image aligncenter size-large\"><figcaption>Too much zinc can interfere with the body\u2019s ability to absorb key nutrients like copper and iron. <span class=\"credit\">rosinka79 \u2013 stock.adobe.com<\/span><\/figcaption><\/figure>\n<p>But the answer is not to add copper supplements to your zinc regimen. It\u2019s to lower your zinc intake and keep it within \u201ca normal daily dose,\u201d <a href=\"https:\/\/www.health.com\/copper-zinc-supplements-together-7970206#:~:text=Taking%20Zinc%20and%20Copper%20Supplements%20Together&amp;text=%E2%80%9CThe%20same%20part%20of%20our,you%20could%20potentially%20get%20sick.%E2%80%9D\" target=\"_blank\" rel=\"noopener\">Cohen recently told Health<\/a>.<\/p>\n<p>Most people don\u2019t need to take additional supplements because their bodies get enough of these nutrients, including zinc and copper, from their diets. But there may be specific cases where zinc and copper are prescribed together by a doctor.<\/p>\n<h2 class=\"wp-block-heading\"><strong>4. Calcium + iron<\/strong><\/h2>\n<p>Though many women in particular have been advised to boost their calcium and iron intake, the combination can be problematic for the brain.<\/p>\n<p>Similar to the way zinc can interfere with copper absorption, calcium can do the same for iron when the two are taken together. Unstable iron levels bouncing from too little to too much can cause what one doctor recently described to Direct Message News as \u201c<a href=\"https:\/\/dmnews.com\/dmn-a-neurologist-says-certain-supplement-combinations-millions-take-daily-may-actually-be-accelerating-brain-aging\/\" target=\"_blank\" rel=\"noopener\">metabolic noise<\/a>,\u201d or stress on the tissues of the brain.\u00a0\u00a0<\/p>\n<p>This can lead to the gradual degradation of the brain\u2019s elasticity, or what some neurologists are newly calling \u201csupplement-induced accelerated aging.\u201d<\/p>\n<\/p><\/div>\n<p><br \/>\n<br \/><a href=\"https:\/\/nypost.com\/2026\/02\/26\/health\/four-supplement-combos-that-are-bad-for-your-brain\/\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Not all supplements are super for your health. In fact, in the wrong dose or combined with the wrong stuff, some supplements can actually do more&hellip;<\/p>\n","protected":false},"author":1,"featured_media":6239,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[42],"tags":[],"class_list":["post-6238","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-wellness"],"_links":{"self":[{"href":"https:\/\/foreignnewstoday.com\/index.php?rest_route=\/wp\/v2\/posts\/6238","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/foreignnewstoday.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/foreignnewstoday.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/foreignnewstoday.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/foreignnewstoday.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=6238"}],"version-history":[{"count":0,"href":"https:\/\/foreignnewstoday.com\/index.php?rest_route=\/wp\/v2\/posts\/6238\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/foreignnewstoday.com\/index.php?rest_route=\/wp\/v2\/media\/6239"}],"wp:attachment":[{"href":"https:\/\/foreignnewstoday.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=6238"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/foreignnewstoday.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=6238"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/foreignnewstoday.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=6238"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}